INDICATIONS AND USAGE Oxycodone hydrochloride tablets are an opioid agonist indicated with the administration of discomfort severe ample to involve an opioid analgesic and for which substitute treatment options are insufficient. (1)Conversion from Mounted-Ratio Opioid/Acetaminophen, Opioid/Aspirin, or Opioid/Nonsteroidal Mix Drugs When changing cli